lunduniversity.lu.se

Education in Chemistry

Lund University

Organic Chemistry - Advanced Course, 15 credits

KEMM01 Organic Chemistry - Advanced Course is replaced by KEMM21 Advanced Organic Chemistry from spring term 2020.

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Aim

The aim of the course is to give advanced knowledge in synthetic organic chemsitry and knowledge in physical organic chemistry

Knowledge and understanding

Be able to identify and and name important organic reactions.

Be able to in detail explain the outcome of organic reactions.

Skill

Be able to plan and evaluate multi-step organic reaction sequences using elementar retrosynthetic analysis

Be able to describeorganic chemical reactions in terms of frontier orbital  analysis

Be able to discuss orally and in writing organic reactions with regrad to mechanisms and selectivity

Be able to suggest alternative reagents and reactions for performing desired organic transformations

Be able to suggest methods to investigate mechanims of reactions

Content

The course deals primary with organic chemical reactions for the creation of C-C bonds emphasising enolate chemistry but also using pericyclic reactions and radical chemistry.  The course gives also advanced knowledge in oxidations and reduction reactions in organic chemistry. The emphasis is on the different chemo-, regio- and diastereoselectivity of the different reaction types. Fundamental retrosynthetic anlysis of target molecues is taught as means to design mutistep synthesis. The course is foucsed on applying a mechanistic approach to understand the outcome of chemical reactions and to emphasise this, the ractions are analyzed using basic forntier orbital analysis. A large part of the course treats methods to elucidate mechansims of reactions such as linear free enery relationships and the primary isotope effect.

An important aspect of the course is to orally present organic reactions to other students. The role of organic chemsitry and in metaril science will be presented.

The laborations are mandatory and are aiming at the illustration of parts of the theoretical contents of the course as well as teaching advanced experimental methodology. Emphasis is given to independence in the planning of each experiment, analysis of the products and critical judgement of literatur syntheses.

Actualities

Basic revision of previous course, KEMB01, see attached revision set.

Exercise 0. Revision KEMB01

For course content KEMB01, see its homepage.

KEMB01

KEMM01

Course Coordinator

Kenneth Wärnmark
046-222 82 17
Kenneth.Warnmark@organic.lu.se

Course literature

Clayden J., Greeves N. and Warren S.
Organic Chemistry, 2nd edition
Oxford University Press 2012

Course Representatives