The course is worth 15 credits and runs full time during the second half of the autumn semester.
The course aims to give insights into protein structure, how it can be modelled and experimentally determined. We start by discussing the forces that drive proteins to fold into three-dimensional structures. Then we look at different databases and discuss homology modelling, i.e. how one can model a protein's three-dimensional structure if one knows the structure of a sufficiently related protein. We also look at some of the most important experimental methods to determine the structure of proteins in different ways: X-ray crystallography, small-angle X-ray scattering and neutron crystallography. We describe how structural information on proteins can be used to develop better pharmaceuticals. The course includes site visits to Lund Protein Production Facility and MAX IV.
The course use the teaching plattform Canvas to communicate with students registered on the course.
All available course material can be found on Canvas.