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KEMM25 Structural biochemistry

The course is worth 15 credits and runs full time during the second half of the autumn semester.

The course aims to give insights into protein structure, how it can be modelled and experimentally determined. We start by discussing the forces that drive proteins to fold into three-dimensional structures. Then we look at different databases and discuss homology modelling, i.e. how one can model a protein's three-dimensional structure if one knows the structure of a sufficiently related protein. We also look at some of the most important experimental methods to determine the structure of proteins in different ways: X-ray crystallography, small-angle X-ray scattering and neutron crystallography. We describe how structural information on proteins can be used to develop better pharmaceuticals. The course includes site visits to Lund Protein Production Facility and MAX IV.

Schedule

NOTE! The schedule for autumn 2021 is preliminary!

Course material and communication

Online course material, course communication and other information can be found on Canvas. You will have access to the course in Canvas after you have been registered. 

Material concerning, primarily, the homology model section of the course:

Protein structures

In case of absence

In case you are ill or will miss mandatory classes for any other reason you should report this to the course responsible teacher (Derek Logan) and the course assistant (Ipsita Banerjee). 

Course Coordinator

Derek Logan
046-222 14 43
Derek.Logan@biochemistry.lu.se

Course literature

Compendium

Other lecturers

Ingemar André
046-222 44 70
Ingemar.André@biochemistry.lu.se

Salam Al-Karadaghi
046-222 45 12
Salam.al-karadaghi@biochemistry.lu.se

Susanna Horsefield
046-222 45 84
Susanna.Horsefield@biochemistry.lu.se

Kristofer Modig
046-222 81 73
Kristofer.Modig@biochemistry.lu.se

Esko Oksanen
046-222 14 48
Esko.Oksanen@biochemistry.lu.se

Course assistant

Course representative